Is the Vertex Pharmaceuticals CEO Overpaid?
On pay-for-performance, Vertex Pharmaceuticals scores A (100/100) on the CEOPay rubric: Reshma Kewalramani earned $12.0M in 2025 while the company posted a 88.7% three-year total shareholder return — meaning pay is broadly aligned with shareholder returns. "Overpaid" is ultimately a judgment, but the grade puts the pay package next to the results it was meant to reward.
This page answers a common executive-compensation question: Is the Vertex Pharmaceuticals CEO Overpaid?. The answer draws on SEC DEF 14A proxy statements, the public disclosure mechanism for U.S. public-company executive pay. Every public company must file an annual proxy statement disclosing CEO and named-executive-officer compensation in detail. Why this matters for shareholders: executive compensation is the single most-disclosed governance metric at U.S. public companies, and the Dodd-Frank-mandated say-on-pay vote gives shareholders an explicit channel to express approval or dissent. Reading pay data well — including pay-versus-performance, peer-group selection, and time-vesting structures — is a basic part of stock-by-stock fundamental analysis.
The detailed answer below uses the actual proxy-statement filings, explains how to read them, and translates the executive-compensation accounting into the shareholder-relevant interpretation.
Vertex Pharmaceuticals Pay-for-Performance Scorecard
- Pay-for-Performance grade
- A (100/100)
- 3-yr shareholder return
- 88.7%
- 3-yr revenue growth
- 55.3%
- Say-on-pay approval
- 95.8%
- CEO total comp
- $12.0M
- CEO-to-worker ratio
- 96:1
Source: Vertex Pharmaceuticals SEC DEF 14A proxy statement. Pay-for-Performance grade is CEOPay's proprietary score (TSR alignment 40%, revenue-vs-pay growth 30%, say-on-pay 20%, pay ratio vs peers 10%).
The CEOPay Pay-for-Performance Score grades Vertex Pharmaceuticals a A (100/100). It weighs four factors pulled from the company's SEC filings: three-year total shareholder return alignment (100/100), revenue growth versus compensation growth (100/100), say-on-pay vote support (100/100), and CEO-to-worker pay ratio versus peers (100/100). Reshma Kewalramani's $12,000,000 package is the number those factors judge.
Over the trailing three years, Vertex Pharmaceuticals delivered 88.7% total shareholder return on 55.3% revenue growth, and 95.8% of shareholders approved the pay plan in the most recent say-on-pay vote. Returns at that level make the package defensible on the numbers — the pay broadly tracked what shareholders earned.
There is no single threshold for "overpaid." The package only pays out in full if performance and vesting conditions are met, and equity dominates it: $6,000,000 of Reshma Kewalramani's 2025 pay came from stock awards versus $1,200,000 in base salary. Reasonable shareholders weigh the grade, the say-on-pay vote, and the peer-group context together rather than the headline number alone.
Pay & Performance Data
| Component | Amount |
|---|---|
| Total Compensation | $12,000,000 |
| Base Salary | $1,200,000 |
| Stock Awards | $6,000,000 |
| Option Awards | $1,440,000 |
| Non-Equity Incentive | $1,800,000 |
| CEO-to-Worker Pay Ratio | 96:1 |
| Pay-Performance Grade | A |
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Frequently Asked Questions
On pay-for-performance, Vertex Pharmaceuticals scores A (100/100) on the CEOPay rubric: Reshma Kewalramani earned $12.0M in 2025 while the company posted a 88.7% three-year total shareholder return — meaning pay is broadly aligned with shareholder returns. "Overpaid" is ultimately a judgment, but the grade puts the pay package next to the results it was meant to reward.
Our Pay-for-Performance Score rates Vertex Pharmaceuticals as A (100/100), based on three-year total shareholder return of 88.7%, revenue growth of 55.3%, and shareholder say-on-pay vote approval.
Reshma Kewalramani, CEO of Vertex Pharmaceuticals, earned $12.0M in total compensation in 2025, including $6.0M in stock awards and $1,200,000 in base salary.
Vertex Pharmaceuticals's CEO-to-worker pay ratio is 96:1. CEO Reshma Kewalramani earns approximately 96 times the median worker's pay of $125,000, as disclosed in the company's SEC DEF 14A proxy statement.
Reshma Kewalramani is the chief executive officer of Vertex Pharmaceuticals (VRTX).
More about Vertex Pharmaceuticals
On pay-for-performance, Vertex Pharmaceuticals scores A (100/100) on the CEOPay rubric: Reshma Kewalramani earned $12.0M in 2025 while the company posted a 88.7% three-year total shareholder return — meaning pay is broadly aligned with shareholder returns. "Overpaid" is ultimately a judgment, but the grade puts the pay package next to the results it was meant to reward.
Source: SEC EDGAR DEF 14A proxy statements, 2026.